Statistical shape models & simulation

Predict the performance of medical devices with virtual patient cohorts

In collaboration with

Virtual Patient Cohorts

Benefit from our collaboration with Materialise: Create synthetic cohorts based on statistical shape models, simulate and optimize your products

Patients come in all shapes and sizes. It is important for medical device manufacturers to understand the different shapes and sizes when creating a new implant or medical device. 

With our physics-based modeling and the statistical shape models of Materialise we can help you to optimize your implants or product family in the entire virtual target population to investigate how these anatomical shape variations may affect the performance and safety of your device. In addition, identify the potential for design optimization and material selection by conducting parameter analyses.


covered without virtual patients


of ethnicities, gender and age potentially covered with virtual patient cohorts

How to benefit from Virtual Patients?

Virtual Patient Cohorts at a glance

Target: Combine statistical shape models with physics based simulation

personalized medicine for health care providers, advancing personalized medicine with simq for clinical trials and more

Articles & publications

Application of patient-specific simulation workflow for obstructive sleep apnea diagnosis and treatment with a mandibular advancement device

International Journal for Numerical Methods in Biomedical Engineering

Experimental study on the influence of model variations on the airway occlusion of an obstructive sleep apnea patient

Journal of Biomechanics

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